Explore a range of resources related to our PAXgene tubes, kits and devices, including handbooks (instructions for use), brochures, technical notes and posters. View or download these documents to find out more about the full line of PAXgene products.
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A New Tissue Fixative for Biomarker Discovery: Gene Expression and miRNA in PAXgene Tissue-fixed, Paraffin-embedded (PFPE) Colorectal Cancer (CRC) and Breast Cancer Tissue vs. Formalin-fixed, Paraffin-embedded (FFPE) Tissue (Groelz 2011)
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Posters
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Taavela, J. et al. (2019) Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsies. BMC Gastroenterol 19, 189 (2019).
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Simultaneous Purification of Genomic DNA and Total RNA, including miRNA, from Sections of PAXgene Tissue-fixed, Paraffin-embedded (PFPE) Tissue
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Supplementary Protocols
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Gillard, M. et al. (2015) Next-gen tissue: preservation of molecular and morphological fidelity in prostate tissue. Am. J. Transl. Res. 7, 1227.
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Preservation of Gene Expression Profile and Histomorphology in Human Breast Tumor Tissue with the New PAXgene Tissue System (Groelz 2010)
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Posters
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Manual Processing of Tissue Specimens Treated with the PAXgene Tissue System
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Supplementary Protocols
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Hara, K. et al. (2015) Surgical Specimens of Colorectal Cancer Fixed with PAXgene Tissue System Preserve High-Quality RNA. Biopreserv. Biobank. 13, 325. doi: 10.1089/bio.2014.0101
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Cryo-embedding Tissue Specimens Fixed and Stabilized with the PAXgene Tissue System
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Supplementary Protocols
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Morphological, Epigenomic and Mutational Analyses of PAXgene Tissue-fixed, Paraffin-embedded (PFPE) Colorectal Cancer (CRC) Specimens — Comparison to Formalin-fixed, Paraffin-embedded (FFPE) and Snap-frozen Samples (Groelz 2010)
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Posters
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Gündisch, S. et al. (2014) Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. Virchows Arch. 465, 509. doi: 10.1
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728 KB
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Can we preserve morphology and nucleic acid integrity for molecular pathology? (Mathieson 2010)
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Posters
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Long-term Storage of TIssue Specimens at –20°C to –80°C with Preservation of Morphology and Nucleic Acids Within Frozen Tissue (Groelz 2009)
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Posters
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Groelz, D. et al. (2013) Non-Formalin Fixative versus Formalin-fixed Tissue: A Comparison of Histology and RNA Quality. Exp. Mol. Pathol. 94, 188. doi: 10.1016/j.yexmp.2012.07.002
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Gündisch, S. et al. (2013) The PAXgene Tissue System Preserves Phosphoproteins in Human Tissue Specimens and Enables Comprehensive Protein Biomarker Research. PLoS One 8, e60638. doi: 10.1371/jou
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934 KB
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Preservation of Histomorphology and Nucleic Acids in Human Breast Tumor TIssue with the New PAXgene Tissue System — A Study with Comparison to Formalin Fixation (Groelz 2009)
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Posters
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765312, 765512, 766134 | Posters |