Like blood, bone marrow specimens are subject to post-collection changes in gene transcription profiles caused by gene regulation (e.g., induction, repression) and RNA degradation.
The PAXgene Bone Marrow RNA System combines patented stabilization chemistry and an optimized purification procedure to isolate high-quality intracellular RNA from bone marrow aspirates (BMA) for an accurate picture of the gene transcription profile at the point of collection.
Easily integrated into standard collection procedures. Simply introduce a 2 ml sample of the collected BMA into the PAXgene Bone Marrow RNA Tube.
Effective stabilization of RNA. A patented additive rapidly and efficiently stabilizes intracellular RNA the moment that the sample is added to the PAXgene Bone Marrow RNA Tube, enabling in vivo transcription profile analysis even after specimen storage.
A standardized workflow for accurate and reproducible results. The optimized chemistry of the PAXgene Bone Marrow RNA Kit purifies RNA with high purity and integrity. Together, tubes and kit are an integrated system for a complete, standardized workflow, from specimen collection to pure RNA.