Explore a range of resources related to our PAXgene tubes, kits and devices, including handbooks (instructions for use), brochures, technical notes and posters. View or download these documents to find out more about the full line of PAXgene products.
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Morphological, Epigenomic and Mutational Analyses of PAXgene Tissue-fixed, Paraffin-embedded (PFPE) Colorectal Cancer (CRC) Specimens — Comparison to Formalin-fixed, Paraffin-embedded (FFPE) and Snap-frozen Samples (Groelz 2010)
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Gündisch, S. et al. (2014) Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. Virchows Arch. 465, 509. doi: 10.1
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Can we preserve morphology and nucleic acid integrity for molecular pathology? (Mathieson 2010)
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Long-term Storage of TIssue Specimens at –20°C to –80°C with Preservation of Morphology and Nucleic Acids Within Frozen Tissue (Groelz 2009)
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Groelz, D. et al. (2013) Non-Formalin Fixative versus Formalin-fixed Tissue: A Comparison of Histology and RNA Quality. Exp. Mol. Pathol. 94, 188. doi: 10.1016/j.yexmp.2012.07.002
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Gündisch, S. et al. (2013) The PAXgene Tissue System Preserves Phosphoproteins in Human Tissue Specimens and Enables Comprehensive Protein Biomarker Research. PLoS One 8, e60638. doi: 10.1371/jou
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Preservation of Histomorphology and Nucleic Acids in Human Breast Tumor TIssue with the New PAXgene Tissue System — A Study with Comparison to Formalin Fixation (Groelz 2009)
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Lonsdale, J. et al. (2013) The Genotype-Tissue Expression (GTEx) project. Nature Genetics 45, 580. doi: 0.1038/ng.2653
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New Fixation Technology for Simultaneous Preservation of Mophology and Nucleic Acids in Tissue (Groelz 2008)
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Kap, M. et al. (2013) Inactivation of Influenza A virus, Adenovirus, and Cytomegalovirus with PAXgene Tissue Fixative and Formalin. Biopreserv. Biobank. 11, 229. doi: 10.1089/bio.2013.0010
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Staff, S. et al. (2013) Preservation of nucleic acids and tissue morphology in paraffin-embedded clinical samples: comparison of five molecular fixatives. J. Clin. Pathol. 66, 807. doi: 10.1136/jc
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Baker, M. (2012) Biorepositories: Building better biobanks. Nature 486, 141. doi: 10.1038/486141a
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Viertler, C. et al. (2012) A New Technology for Stabilization of Biomolecules in Tissues for Combined Histological and Molecular Analyses. J. Mol. Diagn. 14, 458. doi: 0.1016/j.jmoldx.2012.05.002
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Kap, M. et al. (2011) Histological Assessment of PAXgene Tissue Fixation and Stabilization Reagents. PLoS ONE 6, e27704. doi: 10.1371/journal.pone.0027704
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Ergin, B. et al. (2010) Proteomic analysis of PAXgene-fixed tissues. J. Proteome Res. 9, 5188. doi: 10.1021/pr100664e
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