September 2024
A recent publication in the renowned journal Clinical Chemistry by researchers from the Medical University of Graz and CBmed highlights the value of integrating preanalytical ISO and CEN/TS standards in clinical liquid biopsy studies. The study specifically used PAXgene Blood ccfDNA Tubes for blood collection and cell-free DNA (cfDNA) stabilization and isolation from plasma, following the international standard ISO 20186-3:2019.
Principal investigator Prof. Amin El-Heliebi emphasizes: "The advantage of applying the standards is that even challenging hemolytic patient samples can still produce high-quality circulating tumor DNA (ctDNA) or circulating tumor cell (CTC) data."
Discover how these advancements can enhance cancer diagnostics and read the open-access publication!
Clinical Application of ISO and CEN/TS Standards for Liquid Biopsies—Information Everybody Wants but Nobody Wants to Pay For
Lilli Bonstingl, Christina Skofler, Christine Ulz, Margret Zinnegger, Katja Sallinger, Julia Schönberger, Katharina Schuch, Karin Pankratz, Anatol Borrás-Cherrier, Visnja Somodi, Peter M Abuja, Lisa Oberauner-Wappis, Tina Moser, Ellen Heitzer, Thomas Bauernhofer, Thomas Kroneis, Amin El-Heliebi
Clinical Chemistry, Volume 70, Issue 9, September 2024, Pages 1140–1150,