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PAXgene Blood RNA Tube

Collection of whole blood for molecular diagnostic testing
    Kit
    Kit Content
    Catalog No.
    PAXgene Blood RNA Tube (100) 100 Blood collection tubes (2.5 ml). Use with the PAXgene Blood RNA Kit (50) 762165 (BD)

    The PAXgene Blood RNA System* consists of a blood collection tube (PAXgene Blood RNA Tube) and nucleic acid purification kit (PAXgene Blood RNA Kit). It is intended for the collection, storage, and transport of blood and stabilization of intracellular RNA in a closed tube and subsequent isolation and purification of intracellular RNA from whole blood for RT-PCR used in molecular diagnostic testing.

    Performance characteristics for the PAXgene Blood RNA System have only been established with FOS and IL1B gene transcripts. The user is responsible for establishing appropriate PAXgene Blood RNA System performance characteristics for other target transcripts.

    The collection of whole blood is the first step in many molecular assays used to study intracellular RNA. A major challenge in this type of testing is the instability of intracellular RNA, which rapidly degrades within hours after blood collection. Furthermore, certain species of RNA, through the process of gene induction, increase in vitro after blood collection. Both in vitro RNA degradation and gene induction can lead to an under- or overestimation of in vivo relative gene transcript number.

    The PAXgene Blood RNA Tube contains an additive that stabilizes the in vivo gene transcription profile by reducing in vitro RNA degradation and minimizing gene induction. When used in conjunction with one of the PAXgene Blood RNA Kits, the PAXgene Blood RNA Tube provides pure RNA for accurate detection and quantification of gene transcripts.

    Order information:

    BD
    Catalog number: 762165

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    *For in vitro diagnostic use. The PAXgene Blood RNA System consists of a blood collection tube (PAXgene Blood RNA Tube) and nucleic acid purification kit (PAXgene Blood RNA Kit). It is intended for the collection, storage, and transport of blood and stabilization of intracellular RNA in a closed tube and subsequent isolation and purification of intracellular RNA from whole blood for RT-PCR used in molecular diagnostic testing.

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