The PAXgene Blood miRNA System is an enabling technology that consolidates and integrates the key steps of whole blood collection, nucleic acid stabilization, and RNA purification including small RNA species (>18 nt). By minimizing the unpredictability associated with RNA processing, the system provides enhanced accuracy of all intracellular RNAs (miRNA, mRNA, and other functional RNA species) analysis.
Blood Collection
The PAXgene system is standardized on convenient BD Vacutainer® technology, enhancing patient and health care worker safety, providing sample protection, and facilitating consistent blood volumes.
Stabilization
The PAXgene Blood RNA Tube contains a proprietary reagent that immediately stabilizes intracellular RNA for 3 days at room temperature (18–25°C) and 5 days at 2–8°C. The ability to batch samples, minimize processing, and eliminate freezing urgency greatly enhances lab efficiency and made this technology widely used in expression analysis based on blood.
Purification
The PAXgene Blood miRNA Kit uses a unique version of QIAGEN’s proven separation and purification technology. The purification process and chemistry is designed to provide high quality RNA, including miRNAs and other small RNA species as well as larger RNAs, from samples that have been stabilized in the PreAnalytiX reagent.
Standardization
The PAXgene Blood miRNA System provides pharmaceutical, CRO, and research institutions with a completely integrated approach to RNA purification. No special kits. No uncertainty. One integrated product — from blood collection to pure RNA.
